Banca de DEFESA: SERGIO ARAUJO ANDRADE

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : SERGIO ARAUJO ANDRADE
DATE: 02/09/2021
TIME: 13:30
LOCAL: Campus Centro Oeste
TITLE:

NEW APPLICATIONS OF FIELD OPTICAL FLUORESCENCE IN THE DIAGNOSIS OF ORAL PATHOLOGIES

KEY WORDS:

Oral diagnosis; Optical fluorescence; Oral Pathology.

PAGES: 251
BIG AREA: Multidisciplinar
AREA: Biotecnologia
SUMMARY:

Oral diseases affect about 90% of the world population, generating high socioeconomic impact. In this sense, dental caries and periodontal diseases are among the most prevalent diseases, whereas oral cancer is listed as one of the pathologies with the highest morbimortality. Thus, public health policies that aim to reduce the economic impact of health expenditures, through less invasive treatments that contribute to low morbimortality, need to include screening measures and early diagnosis of oral pathologies. However, the conventional clinical examination, which is considered the gold standard for screening oral lesions, has resulted in poor detection rates for oral cancer due to the absence of signs in early stages or the similarity of the signs with that of others benign oral pathologies hindering detection and differential diagnosis. Thus, literature and governmental health regulatory agencies have suggested the use of the widefield optical fluorescence examination as a complementary examination to the conventional clinical examination for screening lesions and determining surgical margins within the context of potentially malignant disorders and oral cancer. In this sense, objectives of this study were to evaluate the application of the use of widefield optical fluorescence beyond to the context of potentially malignant disorders, including the periodic follow-up of patients with a history of oral lesions in a clinical routine and in support to the differential diagnosis. To this end, patients were examined on demand in a public service for oral diagnosis, with acquisition of images under visible light and widefield optical fluorescence and, in suspected cases, a biopsy was performed. Thus, the results show the use of the technique as an aid in the screening and diagnosis of oral squamous papilloma, hairy tongue, mucosal vitiligo, amalgam tattoo, oral cancer and changes related to dental hard tissue and restorations. In this context, it is concluded that the complementary examination of widefield optical fluorescence allows a range of possibilities for clinical applications in the dental routine in a safe, fast and non-invasive way.

BANKING MEMBERS:
Presidente - 1422156 - FERNANDO DE PILLA VAROTTI
Interno - 2875448 - RALPH GRUPPI THOME
Externo ao Programa - 1716137 - HELIO BATISTA DOS SANTOS
Externa à Instituição - SILMARA NUNES ANDRADE - UEMG
Externa à Instituição - AMANDA LUISA DA FONSECA - UNA