Banca de DEFESA: MARINA VIEIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : MARINA VIEIRA
DATE: 13/10/2021
TIME: 14:00
LOCAL: Plataforma Online - GOOGLE MEET
TITLE:

Cosmetics use for the management  of palm – plantar erythrodysesthesia (hand-foot syndrome) in cancer patients: a systematic review and data collection instrument validation

KEY WORDS:

Hand-Foot Syndrome. Antineoplastic Agents. Cosmetics.

PAGES: 60
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUMMARY:

Introduction: Câncer term is restricted to a single word that addresses more than 100 different types of malignant diseases, which have in common the disordered growth of cells, with ability to migrate and invade adjacent tissues or even distant organs. Disease capable of reaching and affecting populations in worldwide, regardless of age, gender, socioeconomic status, family arrangement or education. It is classified as a non-communicable chronic disease, and these presentes a global health problem, generating, in addition to a high number of premature deaths, a loss in life quality, associated with a limitation and incapacity degree. The cancer treatment focus is often restricted to the disease, with dermatological and self-image effects taking second place, in other words, cancer treatment has the primary objective in control and/or eliminating cancer cells. However, it is common that treatment be accompanied by adverse reactions related to the pathology itself or proposed treatment. Objective(s): To carry out an articles systematic review, with clinical approach, related to the prevention and/or management of  hand-foot syndrome, considering the cosmetic preparation use and to develop and validate an instrument to assess the patients life quality with erythrodysesthesia palmoplantar (hand-foot syndrome) with specialists. Materials and methods: The first stage of work was a systematic literature review in five different databases: Scopus, Web of Science, Science Direct, Pubmed and Virtual Health Library (VHL). Different Mesh descriptors were combined using a Boolean operator. The search and preparation of this review followed the guidelines proposed by PRISMA recommendation. Then, a data collection instrument was developed and submitted to ethics committee CAAE: 40485320.0.0000.5545 and later submitted to validation by judges. Results: The search strategy in databases and the selection process resulted in a total of 10 articles eligible for review. Among these studies selected so far, it was believed that the hand-foot syndrome was associated with capecitabine-based chemotherapy and that the effective syndrome clinical management was the chemotherapy dose interruption or reduction. In view of the results presented by study, hand-foot syndrome management with cosmetics was more advantageous than pharmacological management, with urea being chosen as the best moisturizer with an ability to delay syndrome development and to regress levels already installed. Conclusion: In all studies described in this review there was no need to discontinue chemotherapy and some presented cases of syndrome degree regression with cosmetics use, thus, cosmetic management, in addition to circumventing treatment side effect, also improves the patient's quality of life.

 

BANKING MEMBERS:
Externa à Instituição - ANA LUIZA CHAVES MAIA - SS18
Presidente - 1772600 - CARLOS EDUARDO DE MATOS JENSEN
Interno - 2972179 - MARCELO GONZAGA DE FREITAS ARAUJO