Banca de DEFESA: LUDMILA DE PAULA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : LUDMILA DE PAULA
DATE: 30/08/2022
TIME: 08:00
LOCAL: Videoconferência: https://meet.google.com/knj-ugto-eij
TITLE:

FREQUENCY OF ESKAPEE GROUP BACTERIA IN AN INTENSIVE CARE UNIT OF A REFERENCE HOSPITAL IN INFECTOLOGY IN MINAS GERAIS

KEY WORDS:

Healthcare-related infections, Intensive care unit, Prevalence, Epidemiology, Antimicrobial resistance.

PAGES: 106
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Health Care-Related Infections (HAI) represent a public health problem, especially in relation to those caused by antimicrobial-resistant bacteria in intensive care units (ICU). HAIs are responsible for high rates of morbidity, longer hospital stay and mortality. The main bacteria causing HAI are Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aerugionosa, Enterobacter spp., and Escherichia coli belonging to the acronym ESKAPEE. In this context, the objective of this study was to estimate the prevalence of HAIs caused by bacteria of the ESKAPEE group in an adult ICU of a referral hospital in infectology in Minas Gerais. This is a cross-sectional study developed with 77 patients admitted to the ICU with a diagnosis of HAI caused by bacteria from the ESKAPEE group with microbiological evidence from January 1, 2017 to December 31, 2019. Data were collected from a search in the Hospital Management Integrated System (SIGH) and by active search in printed sheets in the Hospital Infection Control Service and in the Microbiology Laboratory. The comparison between groups (ESKAPEE and patients who had HAI) was made using the mean and standard deviation for the variable “age” and the difference in the mean between the groups was investigated using the Student's t test. Categorical variables were compared between groups using Pearson's chi-square test. The significance level adopted was 5%. A total of 1081 patients hospitalized during the study period were obtained. Of these, 112 patients had HAIs with microbiological evidence, and the overall prevalence of HAIs diagnosed by the SCIH was 10.36%. Of the total of 77 patients diagnosed with HAI by ESKAPEE, 50 (64.94%) were multidrug-resistant. No statistically significant associations were found between all variables analyzed. The mean age of patients who had HAI caused by bacteria from the ESKAPEE group was 47.97 years. All patients in the research used at least one invasive procedure, with the blood stream being the most affected site of infection in the ESKAPEE group. The microorganisms isolated from HAI caused by bacteria of the ESKAPEE group belong, for the most part, to the group of Gram-negative bacteria (87.60%). The most prevalent bacterial species of the ESKAPEE group were: Acinetobacter baumannii 26 (26.80%), then Klebsiella pneumoniae 23 (23.70%), Pseudomonas aeruginosa 23 (23.70%). The most prescribed classes of antimicrobials were glycopeptides followed by polymyxins. There vii was an expressive prevalence of HAI caused by Gram-negative bacteria and the most affected site was bloodstream infection. This result suggests a reassessment of the protocols and continuing education of health professionals.

BANKING MEMBERS:
Presidente - 1742677 - JAQUELINE MARIA SIQUEIRA FERREIRA
Interna - 2059540 - ROBERTA CARVALHO DE FIGUEIREDO
Externa ao Programa - 1581671 - MAGNA CRISTINA DE PAIVA
Externo à Instituição - ADRIANO GUIMARAES PARREIRA - UEMG