BIOCHEMICAL CHANGES CHARACTERISTICS OF AGING IN PEOPLE LIVING WITH HIV
Aging, HIV, Biomarkers
HIV infection is a serious public health problem worldwide. The number of elderly people living with HIV has increased rapidly, due to the success of antiretroviral therapy and changes in lifestyle. Chronic inflammation caused by HIV and the effects of antiretroviral therapy has been linked to the premature aging of these individuals. There is no consensus on the age that the individual with HIV is considered elderly, there are differences in a cutoff point. This study aims to assess, through biomarkers, aging in people living with HIV. This is a cross-sectional study carried out with people living with HIV treated at the Specialized Service of Divinópolis-MG, from October 2019 to March 2020. Patients were divided into three age groups: 18 to 49 years , 50 to 59 years old, and over 60 years old, and analyzes were performed to compare the averages / medians of the results of the biochemical tests, in order to characterize the aging process. A significant difference was observed between blood glucose and total cholesterol in the group 18 to 49 years old when compared to the group 50 to 59 years old, and the group over 60 years old. As for creatinine, red blood cells, hemoglobin, hematocrit, the significant difference occurred with the group from 18 to 49 years old, when compared with the group over 60 years old.