Banca de DEFESA: IEDA APARECIDA DINIZ

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : IEDA APARECIDA DINIZ
DATE: 15/12/2023
TIME: 08:30
LOCAL: Videoconferência
TITLE:

EFFECT OF DURATION OF BREASTFEEDING ON HEMOGLOBIN LEVELS OF INFANTS AT TWELVE MONTHS OF AGE: A COHORT STUDY


KEY WORDS:
anemia; exclusive breastfeeding; infant; iron.

PAGES: 99
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:
Initial considerations: It is estimated that the global prevalence of anemia in children aged six
to 59 months in 2019 is 39.8%. In Brazil, the prevalence of anemia in children under seven
years of age was estimated at 33%. Justification: breast milk is considered the best food, but
there is no consensus in the literature about the effect of breastfeeding duration on hemoglobin
levels in children at 12 months of age. Objectives: the main objectives were answered by
subdividing the thesis into sub-studies. Objective of substudy one: to identify, through a
systematic review, the association between the duration of exclusive breastfeeding and iron
deficiency anemia. Objective of substudy two: to analyze the effect of the duration of exclusive
breastfeeding and total duration of breastfeeding on hemoglobin levels in children at 12 months
of age. Methods: substudy one, a systematic literature review, was carried out using PRISMA
recommendations, and search strategies built from the PECO framework. The Rayyan software
was used to read the abstracts, and the methodological quality score proposed by Donws &
Black was used to read in full. The data were analyzed descriptively. Substudy two is a
prospective cohort in which children were followed at birth and then at two, four, six, nine and
12 months. The population consisted of children born in a regional health reference Hospital
Center located in the city of Divinópolis - MG. The sample was calculated at 149 children. In
the first wave, carried out at the Hospital Reference Center, sociodemographic information,
history of anemia, and use of ferrous sulfate during pregnancy were collected. At two and four
months, data was collected via telephone. At six months, data were obtained from mothers at
the Basic Health Unit. At nine months via telephone. At twelve months, part of the collection
was carried out by telephone, the other in the municipal laboratory. Capillary blood samples
were obtained at birth and at six months, and venous blood at 12 months to assess hemoglobin.
The food consumption marker was applied in all waves to verify the duration of breastfeeding.
Information about the use of ferrous sulfate by the child was collected. Comparisons between
the explanatory variables and the hemoglobin level at 12 months were calculated using the
Mann Whitney, Kruskal Wallis and chi-square tests. A non-parametric model, generalized
linear regression model, was used to verify the effect of breastfeeding duration on hemoglobin
levels at 12 months of age. Results: substudy one, published in the journal Acerco em Saúde,
“Duration of exclusive breastfeeding associated with iron deficiency anemia in children: a
systematic review”, considered for the final analysis a total of 28 manuscripts, of which 60.7%
showed an association between the duration of exclusive breastfeeding and anemia. Substudy
two, original article, presents results from the prospective cohort. At six months, 38.5% of
children had hemoglobin lower than 11g/dl. At 12 months this percentage was 22.7%. The
median hemoglobin at six months was 11g/dl (Q1-10.6/ Q3-11.6g/ dl), and at 12 months 11.5
g/dl (Q1-11/ Q3-12.4g/dl). The median duration of exclusive breastfeeding was two months
(Q1-1/Q3-4 months), and the total duration of breastfeeding was twelve months (Q1-6/Q3-12
months). 52.4% of children discontinued exclusive breastfeeding early. The socioeconomic
extracts from ABEP maintained a significant association with hemoglobin values at twelve
months. Final considerations: Children from families with low to medium socioeconomic
status were those who most often had lower hemoglobin levels. New research, especially with
longer follow-up periods, is necessary to reveal the relationship between duration of
breastfeeding and hemoglobin levels

BANKING MEMBERS:
Interna - 1347706 - ALBA OTONI COLLARES
Externo à Instituição - FABRIZIO FURTADO DE SOUSA - UEMG
Externo à Instituição - FLÁVIO DINIZ CAPANEMA - FHEMIG
Presidente - 319693 - JOEL ALVES LAMOUNIER
Externa ao Programa - 1680605 - VIRGINIA JUNQUEIRA OLIVEIRA
Notícia cadastrada em: 01/12/2023 12:43
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