Banca de DEFESA: IEDA APARECIDA DINIZ

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : IEDA APARECIDA DINIZ
DATE: 22/12/2023
TIME: 08:30
LOCAL: https://meet.google.com/qns-ijsr-ytz
TITLE:

Effect of duration of breastfeeding on anemia and hemoglobin levels in children

KEY WORDS:

anemia; breastfeeding; infant; iron, hemoglobin.

PAGES: 99
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Initial considerations: It is estimated that the global prevalence of anemia in children aged six
to 59 months in 2019 is 39.8%. In Brazil, the prevalence of anemia in children under seven
years of age was estimated at 33%. Justification: breast milk is considered the best food, but
there is no consensus in the literature about the effect of the duration of breastfeeding on the
hemoglobin levels of children at 12 months of age. Objectives: the main objectives were
answered by subdividing the thesis into two sub-studies. Objective of substudy one: to identify,
through a systematic review, the association between the duration of exclusive breastfeeding
and iron deficiency anemia. Objective of substudy two: to analyze the effect of the duration of
exclusive breastfeeding and total duration of breastfeeding on hemoglobin levels in children at
12 months of age. Methods: Substudy one, a systematic literature review, was carried out using
PRISMA recommendations, and search strategies built from the PECO framework. The Rayyan
software was used to read the abstracts and the methodological quality score proposed by
Donws & Black was used to read in full. The data were analyzed descriptively. Substudy two is
a prospective cohort in which children were followed at birth and then at two, four, six, nine
and 12 months. The population consisted of children born in a regional health reference Hospital
Center located in the city of Divinópolis - MG. The sample was calculated at 149 children. In
the first wave, carried out at the Hospital Reference Center, sociodemographic information,
history of anemia and use of ferrous sulfate during pregnancy were collected. At two and four
months, data was collected via telephone. At six months, data were obtained frommothers at the
Basic Health Unit. At nine months via telephone. At twelve months, part of the collection was
carried out by telephone, the other in the municipal laboratory. Capillary blood samples were
obtained at birth and at six months, and venous blood at 12 months to assess hemoglobin. The
food consumption marker was applied in all waves to verify the duration of breastfeeding, as
well as information on the use of ferrous sulfate by the child. Comparisons between the
explanatory variables and the hemoglobin level at 12 months were calculated usingthe Mann
Whitney, Kruskal Wallis and chi-square tests. A non-parametric model, generalizedlinear
regression model, was used to verify the effect of breastfeeding duration on hemoglobinlevels
at 12 months of age. Results: substudy one, published in the journal Acervo em Saúde, entitled
“Duration of exclusive breastfeeding associated with iron deficiency anemia in children: a
systematic review”, considered for the final analysis a total of 28 manuscripts, of which 60.7 %
showed an association between the duration of exclusive breastfeeding and anemia. Substudy
two presents results from the prospective cohort. At six months, 38.5% of children had
hemoglobin lower than 11g/dl. At 12 months this percentage was 22.7%. The median
hemoglobin at six months was 11g/dl (Q1-10.6/ Q3-11.6g/ dl), and at 12 months 11.5 g/dl (Q1-
11/ Q3-12.4g/dl). The median duration of exclusive breastfeeding was two months (Q1-1/Q3-
4 months), and the total duration of breastfeeding was twelve months (Q1-6/Q3-12 months).
52.4% of children discontinued exclusive breastfeeding early. The socioeconomic extracts from
ABEP maintained a significant association with hemoglobin values at twelve months. Final
considerations:Children from families with low tomedium socioeconomic statuswere those who
most often had lower hemoglobin levels. New research, especially with longerfollow-up
periods, is necessary to deepen knowledge about the relationship between duration of
breastfeeding and hemoglobin levels.

BANKING MEMBERS:
Interna - 1347706 - ALBA OTONI COLLARES
Externa à Instituição - ARIENE SILVA DO CARMO - MS
Externo à Instituição - FABRIZIO FURTADO DE SOUSA - UEMG
Presidente - 319693 - JOEL ALVES LAMOUNIER
Externa ao Programa - 1680498 - MARCIA CHRISTINA CAETANO ROMANO
Externa ao Programa - 1680605 - VIRGINIA JUNQUEIRA OLIVEIRA