Banca de DEFESA: NÍVEA APARECIDA DE ALMEIDA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : NÍVEA APARECIDA DE ALMEIDA
DATE: 22/09/2021
TIME: 14:00
LOCAL: Videoconferência
TITLE:

EVALUATION OF THE PROFILE OF PATIENTS USING ANTICOAGULANTS DIRECT ORALS ASSISTED JUDICIALLY

KEY WORDS:

Health's Judicialization, Pharmacovigilance, Rivaroxaban, Dabigatran, Anticoagulants, Warfarin

PAGES: 104
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Objective: Evaluate the profile of patients and requests for direct oral anticoagulants (DOACs) assisted through the courts. Methods: Descriptive documental study divided into two articles: (1) Data collection was carried out in Divinópolis of all cases judged with a favorable opinion by the court regarding the request of the DOACs. Data collection was carried out from three secondary sources: court proceedings, patient records and the Health Information System (HIS); (2) The sociodemographic, diagnostic and treatment characteristics of the patients were evaluated, as well as information on the evidence of the technology's efficacy and safety and the conclusion of all Technical Notes (TN) referring to the request for DOACs obtained from the e-NatJus platform. Results: Article 1: A total of 74 processes referring to the request of DOACs in the city of Divinópolis-MG were included in the study. It was observed that 74.3% of the individuals were female, the average age was 70 years. The most common diagnosis was atrial fibrillation (36.5%). About 52.7% of physicians reported that there was a therapeutic attempt with warfarin before the introduction of DOACs and convenience (24.3%) was the most used justification by prescribers for choosing DOACs, followed by difficulty in controlling INR (20, 3%). Another finding was that 25.7% of the patients never obtained the medication requested through the courts at the SUS pharmacy. Article 2: 181 TN were included in the study: rivaroxaban (67%), apixaban (16%), dabigatran (12%) and edoxaban (5%). Approximately 86 TN had similar content in the scientific evidence item. It was observed that 57.5% had an unfavorable conclusion to make the requested medication available. Among the 77 TN that had a favorable conclusion, 57.1% did not evaluate the recommendations of the National Commission for the Incorporation of Technologies. Conclusion: It was observed in most of the analyzed processes and TNs that the medical prescriptions of DOACs were not based on protocols and clinical guidelines established by the SUS to treat the respective clinical conditions, in both studies we found the lack of important information as an obstacle, leaving gaps regarding the real need for the judicialization of these drugs.

BANKING MEMBERS:
Externa à Instituição - RITA CAROLINA FIGUEIREDO DUARTE
Presidente - 1581667 - DANYELLE ROMANA ALVES RIOS
Externa ao Programa - 1296968 - MARIANA LINHARES PEREIRA