Banca de QUALIFICAÇÃO: LUDMILA DE PAULA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : LUDMILA DE PAULA
DATE: 21/10/2021
TIME: 08:30
LOCAL: Videoconferência
TITLE:

HEALTH CARE-RELATED INFECTIONS: PREVALENCE OF ESKAPE GROUP BACTERIA IN A ADULT INTENSIVE CARE UNIT OF A HOSPITAL REFERENCE IN INFECTOLOGY IN MINAS GERAIS

KEY WORDS:

Health care-associated infections, Intensive care unit, Prevalence, Epidemiology, Antimicrobial resistance.

PAGES: 94
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Introduction: Health care-associated infections (HAIs) represent a public health problem, especially in relation to those caused by antibiotic-resistant bacteria in intensive care units (ICU), where they are responsible for high morbidity rates, longer hospital stays and mortality. The main bacteria causing HAIs are Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacteriaceae belonging to the acronym ESKAPE. Objective: The objetive of this study was to estimate the prevalence of ESKAPE group bacteria in an adult ICU of a reference hospital infectology in Minas Gerais. Methodology: This is a cross-sectional study carried out with 90 patients admimtted to the ICU with a diagnosis of HAI due to bacteria from the ESKAPE group with microbiological evidence in the period from January 1, 2017 to December 31, 2019. Data were collected from a search in the Integrated Hospital Management System and byan active search in forms printed at the hospital infection control service and at the Microbiology Laboratory. The comparison between groups (multiresistant and multisensitive ESKAPE) was made using the mean and standard deviation for the variable “age” and the difference in the mean between the groups was investigated using the Student’s t test. Categorical variables were compared between groups using Pearson’s chi-square test. The significance level adopted was 5%. Results: During the collection period, there were 1081 hospitalized patitents. Of these, 112 patients had 145 HAIs, the overall prevalence of HAI diagnosed by the hospital infection control service was 10.4%. Of the total of 90 patients diagnosed with HAI by ESKAPE, 59 (65.6%) were multidrug-resistant and 31 (34.4%) were multisensitive. No statistically significant associations were found between all analyzed variables. The mean age of patients who had HAI in the ESKAPE group was 48.1 years and the median 46 years. All patients in the study used at least one invasive procedure, which was the indwelling urinary catheter. The isolated microorganisms belong, for the most part, to the group of Gram-negative bacteria. The most prevalent antibiotic-resistant bacterial species of the ESKAPE group were: Acinetobacter spp., Klebsiella spp., Enterobacteria. The most prescribed antimicrobial classes were glycopeptides followed by polymyxins. Conclusion: There was an expressive prevalence of HAIs caused by Gram-negative bacteria and the most affected site was bloodstream infection.

BANKING MEMBERS:
Interno - 1676450 - GUSTAVO MACHADO ROCHA
Presidente - 1742677 - JAQUELINE MARIA SIQUEIRA FERREIRA
Externa ao Programa - 1581671 - MAGNA CRISTINA DE PAIVA
Interna - 2059540 - ROBERTA CARVALHO DE FIGUEIREDO