Banca de QUALIFICAÇÃO: ROMMEL LARCHER RACHID NOVAIS

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : ROMMEL LARCHER RACHID NOVAIS
DATE: 27/04/2022
TIME: 08:30
LOCAL: Videoconferência
TITLE:

Evaluation of body composition by imaging methods, anthropometry and bioimpedance in patients from the post COVID 19 outpatient clinic in Divinópolis, MG and its relationship with pathological history and the quality of life

KEY WORDS:

COVID-19; Body Composition; Ultrasonography; Absorptiometry Photon; Bioelectrical Impedance; Anthropometry.

PAGES: 142
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Introduction: COVID-19 is a recent illness that has caused awareness in the scientific community due to its high transmissibility, the variety of the symptoms, and the unknown consequences in long term. Despite that, a worse prognosis between the illness and conditions related to body composition, such as obesity and sarcopenia, has been observed and, therefore, deserves attention, as well as the methods used to measure the body composition. Objectives: To study the quality of life, aspects of the disease, and the body composition of post-covid patients, comparing different methods such as anthropometry, bioimpedance (BIA), and ultrasound (US) with Dual-Energy X-Ray Absorptiometry (DEXA), evaluating The correlation and agreement of these methods. Methods: A observational study was developed, evaluating patients from the post-Covid outpatient in Divinópolis, Minas Gerais, with the collection of data relating to the quality of life, through the SF-36 questionnaire and the body composition, by BIA, anthropometry, ultrasound, And Dexa. Results: Concerning body composition, 44% of patients were classified as obese according to body fat mass index and 8% had an appendicular lean mass index compatible with low muscle mass measured by DEXA. 64% presented substantially increased abdominal circumference. About Covid-19, 47.6% needed hospitalization during the acute phase of the disease, 23.8% required mechanical ventilation, and 90% were already vaccinated. The quality-of-life data revealed that the worst-performance aspect were the limitation by emotional aspects (0.00) and the the physical limitation (25.00) and the best score was mental health (51.05). There was good reproducibility of the measurements of the adipose and muscular tissue by US with ICC greater than 0.90 in all anatomical regions. There was a moderate correlation between the DEXA A / G rate and the circumference of the waist and between the A / G rate with intra-abdominal fat measured by US (ICC = 0.567 and 0.563), respectively. As for lean mass, there was a positive moderate correlation between appendicular muscle mass measured by the US and the appendicular lean mass measured by DEXA, with a Spearman correlation of 0.620. About the percentage of body fat, only BIA presented an agreement with Dexa by the analysis of Bland Altman. Conclusion: Changes to the body composition were frequent, with the quality-of-life data revealing limitations of emotional and physical aspect in patients. Between body composition tests, BIA presented the best performance in the evaluation of adipose tissue compared to the gold standard. More widespread research is needed for the most in-depth knowledge of the characteristics of the postCovid symptomatic population and the validity of methods, such as US to evaluate body adipose tissue. Development and validation of specific equations for our population should be stimulated, positively influencing agreement with Dexa.

BANKING MEMBERS:
Presidente - 1676450 - GUSTAVO MACHADO ROCHA
Externa ao Programa - 1680498 - MARCIA CHRISTINA CAETANO ROMANO
Externo à Instituição - WENDELL COSTA BILA - UEMG